🍄 The $22B Psychedelic Boom

👋 Welcome

Hi friends! What a time to be alive.

This week, we’re watching mushrooms move from myth to medicine, investors bet big on inner space, and scientists ask if belief itself might be the most powerful compound of all. It’s not just hype - it’s a shift, slow and staggering, happening one study, one story, one step at a time.

Thanks for being part of it. Let’s see what’s unfolding.

🔝 Weekly Highlights

• 🍄 Healing on a molecular level – A new review suggests psilocybin may help maximize recovery after traumatic brain injuries. The brain might not change its stripes, but it might learn to paint new ones. Read more
  

• 💼 Biohacker’s 4-step guide to psychedelic therapy – We’ve got a blueprint featuring, and before you think needle-in-the-arm, an off-the-grid, nondrug approach to try first. Check it out
  

• 👁️ Expand your mind—with science – Experts reveal how psychedelics don’t just open doors, they can expand entire walls of perception. What once felt like limits start to look more like invitations. Expand your horizons
  

• ✨ More meaning, less meh – Psychedelic experiences may deliver a durable boost in perceived meaning in life. It’s like having philosophical glow sticks long after the trip. Read the insight

🧬 Quick Hits

RESEARCH 🔬

• 🧘 Mindful waves – Meditation tweaks attention-related brainwaves—turns out, mindfulness is brainwave CrossFit. Details here
  

• 💨 Spray and slay – Esketamine nasal spray delivers fast-acting antidepressant effects—like mood recovery in a bottle. Learn more
  

• 👶 Postpartum reboot – Reunion’s psychedelic prodrug reduces postpartum depression in Phase 2 trials. Baby blues, meet molecular mood magic. Dig deeper

POLICY 🏛️

• 🗳️ Alaska decriminalization on deck – Signature gathering begins for a ballot initiative to decriminalize psychedelics in Alaska. From mushrooms to moose country. Neat details

BUSINESS 📈

• 🧠 Hopkins + Rose Hill = neuro-repair dream team – Psychedelics may soon help restore motor function after brain injuries thanks to this new partnership. Full scoop
  

• 🧪 MindMed in Phase 3 – MM120 enters the final testing stage for treating major depressive disorder. Clinical meets mystical. Read up

CULTURE 🎭

• 🩺 Aspirin vibes incoming – UCI and others push psychedelics toward aspirin-level controversy (and acceptance). Normal’s getting redefined. Take a peek
  

• 🌿 Ayahuasca heals more than hearts – This jungle brew might be your sub-conscious’s best therapist. Full brewdown
  

• 🧠 TBI recovery gets trippy – A man says psychedelics helped him heal from a traumatic brain injury. Maybe neuroplasticity wears a tie-dye cape. His journey

🌈 Main Features

1. 💰 Psychedelics Projected to Hit $22.6 Billion Market by 2033

The global psychedelic drug market is riding a financial rocket ship, now projected to hit $22.6 billion by 2033. That’s not just microdosing your portfolio, that’s a heroic dose for Wall Street. With biotechs scaling, research stacking, and public attitudes quickly thawing, this market boom reflects serious investor confidence.

The report highlights how companies in mental health, trauma, addiction, and even spiritual care are jockeying for shelf space and regulatory greenlights. From ketamine clinics in strip malls to mushroom patents, the field is turning its mysticism into mainstream medicine - with a profit margin.

And while many understandably worry about over-commercialization, advocates say funding equals access. Investment can accelerate research, legitimize treatment, and bring options to people who’ve long been left out of traditional care.

Still, people say the fear remains that profit motives could dilute the deeper purpose, and it needs to be done in a way where healing doesn’t become just another product on the shelf.

👉 Read the report here

2. 🧪 Are Psychedelics Just Fancy Placebos?

Placebo effects are the pranksters of the pharmaceutical world - helping you heal with a wink and no active ingredients. But what happens when psychedelics, already known for their suggestibility and context-dependence, are held up against science’s gold standard: the double-blind placebo trial?

This feature from High Times digs deep into how psychedelics might challenge our entire model of medical testing. When your mind’s own expectations can generate euphoria, insight, or peace - how do we tease apart what’s "real"?

Some researchers argue that the placebo effect isn't a bug in psychedelic trials, it's a feature. These compounds don’t just work despite context - they may only work because of it. That makes psychedelics not anti-scientific, but meta-scientific: medicine that reflects us back to ourselves.

Bottom line? If placebo is the power of belief, and psychedelics enhance that belief to cosmic levels… maybe it’s time to admit the mind was always part of the medicine.

💡 Honorable Mention

🌌 Death vs DMT 

The overlap between near-death visions and DMT trips is both eerie (in a good way) and beautiful. Fractals, tunnels, and ego dissolve like butter in the beyond.

Scientists note uncanny parallels in reported visuals, emotional states, and the classic “life review,” but with key timing and interpretive differences. One may be a cosmic glitch, the other a neurotransmitter blitz, but both ask the same question: What is this thing we call consciousness?

👉 Compare journeys

🎁 Psychedelic Utility Belt

• 🎬 Trip-worthy TV – From kaleidoscopic dramas to mystical mindf**ks, here are the best psychedelic movies and shows to bend your binge brain. Watch list
  

• 🌀 Freedom Conference Alert – Missouri’s entering the psychedelic field with the Psychedelic Freedom Conference. Equal parts grassroots and galactic. September 6 in Springfield, MO - see you there! Register here

👋 Signoff

Psychedelics reveal how fragile and flexible our stories really are.

Whether it’s a personal breakthrough or a policy rewrite, the change always starts the same way: someone asks a better question.

Not “Is this allowed?” but “What else is possible?”

We’re not here to chase trends.

We’re here to rewrite the script - together, messily, and with full permission to laugh through the existential dread.

Stay playful. Stay disruptive. Stay rooted in wonder.

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Thank you for joining us as we continue to navigate this ever-changing landscape.

P.S. Explore what they don’t want you to see - check us out on X (Twitter) and Instagram, and dive deeper into all things psychedelic on our website. 🌐✨