🍄 One Dose to Heal Them All

From lab notes to late-night TV: psychedelic therapy grows louder.

July 01, 2025

👋 Welcome

Happy July, friends!

Some weeks feel like the veil’s just a little thinner - where science confirms the whispers, pop stars speak like therapists, and a single mushroom trip echoes across half a decade. This is one of those weeks.

Whether you’re here for the data, the soul work, or just to feel a little less alone in this weird world, you’re in good company.

🔝 Weekly Highlights

  • 🌏 New Zealand Approves Psilocybin—with One Prescriber — Psilocybin therapy is legal, but only one doctor is allowed to provide it. Bureaucracy meets breakthrough. Meet the Mushroom MD

  • 🎤 Lorde Praises MDMA Therapy — The pop star says it helped her beat stage fright and show up fully. Colbert approves. Feel the shift

  • 🌍 Crisis-Proof Healing — Psychedelics helped ease anxiety and depression during global crises like COVID. Read the findings

🧬 Quick Hits

RESEARCH 🔬

  • 🧠 Your Brain on Psychedelic Self-Talk — Regular users show unique neural patterns when reflecting on themselves. See the scan

  • 👶 Psilocybin for Postpartum Depression? — A Cleveland Clinic study suggests the mushroom may offer fast-acting relief for new moms. Peek the science

POLICY 🏛️

  • 🌿 Iowa Rep Defends Natural Psilocybin — Pushes back on a bill favoring synthetic-only legalization. See what the debate is about

  • 🗳️ Alaska Eyes 2026 Ballot — Advocates launch a push to fully legalize psychedelics. Watch the north star

  • 🎖️ Michigan Offers Psilocybin for PTSD — A new bill aims to legalize access for trauma survivors. Read the proposal

  • ⚖️ New Hampshire Hits a Legislative Pause — A bill to reduce psilocybin penalties passes the House, stalls in Senate. Follow the detour

BUSINESS 📈

  • 💊 Compass Pathways Hits Target, Investors Unphased — The COMP360 trial met its endpoint, but markets weren’t impressed. Get the lowdown

CULTURE 🎭

  • 🏈 NFL Star Tackles OCD with Psychedelics — Braden Smith used them to confront religious scrupulosity before retirement. Clean the slate

  • 🐘 Rick Perry’s Psychedelic Mission — The ex-Texas governor says he’s now fighting for ibogaine to treat addiction. Politics just took a heroic dose. Trip with Perry (it’s an op-ed he wrote behind a paywall, but worth reading if you can)

🌈 Main Features

1. 🍄 One Dose to Heal Them All: Psilocybin’s 5-Year Power

In a long-term follow-up of a 2020 clinical psilocybin trial, Dr. Alan Davis of Ohio State University and their team—noted at Psychedelic Science 2025—found that 67% of participants remained in remission from major depression five years after a single guided dose.

These individuals also reported lasting improvements in anxiety and daily functioning. That kind of durability challenges conventional mental-health models and could force a rewrite of how we train therapists, structure care, and value one-and-done treatments, especially when backed by data from a rigorously tracked cohort.

🕰️ See the science

2. 🧪 Bigger Doses, Bigger Breakthroughs

Turns out when it comes to treating depression with LSD, size might matter. A new study out of the University of Basel found that higher doses of LSD (100–200μg), paired with therapy, led to significantly greater reductions in depression than lower doses (just 25μg). And no—this wasn’t a Burning Man anecdote. It was a randomized, double-blind clinical trial, published in the legit journal Med.

The benefits lasted up to 12 weeks post-treatment, with researchers noting the high-dose group made the most progress. They’re now calling for a larger Phase 3 trial, and the FDA has already granted LSD “breakthrough therapy” status for anxiety. Translation? The molecule once blamed for melting America’s youth may be your psychiatrist’s new favorite prescription pad.

Still, they caution that LSD’s longer duration makes it more resource-intensive than psilocybin. But for those who need a deeper reset, it could be worth the extra hours—and the extra prep. Because with great neuroplasticity comes great responsibility.

📊 Read the data

💡 Secondaries

🕳️ Meta’s Algorithm Is Killing the Vibe – From Instagram takedowns to buried Substacks, psychedelic educators and harm reductionists are being shadow-banned, throttled, and erased.

The algorithm doesn’t care if you're a healer or a meme lord, if you mention psychedelics, you're marked. To make matters worse, it doesn’t seem to matter what kind of safety precautions you take. This isn’t just annoying - it’s existential for grassroots communities trying to share life-saving info.

Shoutout to all of those affected who are standing up and speaking out! 📵 Sound the alarm

🎁 Psychedelic Utility Belt

  • 🌸 The Science of Ayahuasca — What happens to your brain when the vine takes hold? Let’s get molecular. Take the journey

  • 📚 New Drop: Death by Astonishment — Andrew Gallimore’s new book officially drops today and dives into DMT (and what it's doing to us). Read now 

👋 Signoff

That’s a wrap on this journey. If the algorithms are gatekeeping your soul, the Senate’s stalling your mushroom rights, or your shadow work feels more like shadow boxing—just know: we see you.

Stay wild, stay kind, and keep asking questions that make people slightly uncomfortable at dinner parties.

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Thank you for joining us as we continue to navigate this ever-changing landscape.

P.S. Explore what they don’t want you to see - check us out on X (Twitter) and Instagram, and dive deeper into all things psychedelic on our website. 🌐✨